PIMA Multiple Sequence Alignment Results

Maximal Linkage Clustering

pat-ML ((Deubiquitinase2 3990.00 deubiquitinase1) 3372.01 mdeubiquitinase)

Page 1.1
			  1            15 16           30 31           45 46           60 61           75 76           90 
	1 pat-ML	  --------------- MALHrPQYIFGDFSP DEFNQFFVTPRSSVE LPPYSGTgLCjXQAX DpLPDgGQEeQRIEF GVDEVIEPSkjLPXT	75
	2 Deubiquitinase2 --------------- MALHSPQYIFGDFSP DEFNQFFVTPRSSVE LPPYSGTVLCGTQAV DKLPD-GQEYQRIEF GVDEVIEPSDTLPRT	74
	3 deubiquitinase1 REQPEDRGVPMKRAA MALHSPQYIFGDFSP DEFNQFFVTPRSSVE LPPYSGTVLCGTQAV DKLPD-GQEYQRIEF GVDEVIEPSDTLPRT	89
	4 mdeubiquitinase --------------- MALHNPQYIFGDFSP DEFNQFFVTPRSSVE LPPYSGT-LCSIQAE DELPDAGQEHQRIEF GVDEVIEPSEGLPPT	74


Page	2.1
			  91	      105 106	      120 121	      135 136  	      150 151	      165 166	      180 
	1 pat-ML	  PSYSISSTLNPQAPE FILGCTjSKXXPkha rKkXiYjSIDgQYPh SALALkjrSNXEAEX LENDjXjGGLGQRER KKKKKRPPGYYSYLK	165
	2 Deubiquitinase2 PSYSISSTLNPQAPE FILGCTASKITPDGI TKEASYGSIDCQYPG SALALDGSSNVEAEV LENDGVSGGLGQRER KKKKKRPPGYYSYLK	164
	3 deubiquitinase1 PSYSISSTLNPQAPE FILGCTASKITPDGI TKEASYGSIDCQYPG SALALDGSSNVEAEV LENDGVSGGLGQRER KKKKKRPPGYYSYLK	179
	4 mdeubiquitinase PSYSISSTLNPQAPE FILGCTTSKKIPEAV EKDETYSSID-QYPA SALALESNSNAEAET LENDSGAGGLGQRER KKKKKRPPGYYSYLK	163


Page	3.1
			  181	      195 196	      210 211	      225 226	      240 241	      255 256	      270 
	1 pat-ML	  DGGkDSXSjXjLVNG HArSgVjrSXrAgED AEFMgDcXPjVXPRT ClSPQNjXDXaSXXV PDSPFPXjLGjDjRT AGXXEGXXXADFXQj	255
	2 Deubiquitinase2 DGGDDSISTEALVNG HANSAVPNSVSA-ED AEFMGDMPPSVTPRT CNSPQNSTDSVSDIV PDSPFPGALGSDTRT AGQPEGGPGADFGQS	253
	3 deubiquitinase1 DGGDDSISTEALVNG HANSAVPNSVSA-ED AEFMGDMPPSVTPRT CNSPQNSTDSVSDIV PDSPFPGALGSDTRT AGQPEGGPGADFGQS	268
	4 mdeubiquitinase DGGEDSASPATLVNG HATS-VGTSGEAVED AEFM-DVLPPVMPRT CDSPQNPVDFISGPV PDSPFPRTLGGDART AGLCEGCHEADFEQP	251


Page	4.1
			  271	      285 286	      300 301	      315 316	      330 331	      345 346	      360 
	1 pat-ML	  CfPAggggDiLXRTA GjQPfVGTDTTENfh VANGpILESjGEXTA jNGXELHTrEjXDLD PjKPESXSPPAkjjX SASGjcPaSQPgKSW	345
	2 Deubiquitinase2 CFPAEAGRDTLSRTA GAQPCVGTDTTENLG VANGQILESSGEGTA TNGVELHTTESIDLD PTKPESASPPADGTG SASGTLPVSQP-KSW	342
	3 deubiquitinase1 CFPAEAGRDTLSRTA GAQPCVGTDTTENLG VANGQILESSGEGTA TNGVELHTTESIDLD PTKPESASPPADGTG SASGTLPVSQP-KSW	357
	4 mdeubiquitinase CLPA----DSLLRTA GTQPYVGTDTTENFA VANGKILESPGEDTA ANGAELHTDEGADLD PAKPESQSPPAESAL SASGAIPISQPAKSW	337


Page	5.1
			  361	      375 376	      390 391	      405 406	      420 421	      435 436	      450 
	1 pat-ML	  ASLFHDSKPSjSSPc AYVETKfSPPXXSPL XSEKQcEVKEGLVPV SEDPVAIKIAELLEr VTLIHKPVSLQPRGL INKGNWCYINATLQA	435
	2 Deubiquitinase2 ASLFHDSKPSSSSPV AYVETKYSPPAISPL VSEKQVEVKEGLVPV SEDPVAIKIAELLEN VTLIHKPVSLQPRGL INKGNWCYINATLQA	432
	3 deubiquitinase1 ASLFHDSKPSSSSPV AYVETKYSPPAISPL VSEKQVEVKEGLVPV SEDPVAIKIAELLEN VTLIHKPVSLQPRGL INKGNWCYINATLQA	447
	4 mdeubiquitinase ASLFHDSKPSASSPM AYVETKCSPPVPSPL ASEKQMEVKEGLVPV SEDPVAIKIAELLET VTLIHKPVSLQPRGL INKGNWCYINATLQA	427


Page	6.1
			  451	      465 466	      480 481	      495 496	      510 511	      525 526	      540 
	1 pat-ML	  LVACPPMYHLMKFIP LYSKVQRPCTSTPMI DSFVRLMNEFTNMPV PPKPRQALGDKIVRD IRPGAAFEPTYIYRL LTVXKSSLSEKGRQE	525
	2 Deubiquitinase2 LVACPPMYHLMKFIP LYSKVQRPCTSTPMI DSFVRLMNEFTNMPV PPKPRQALGDKIVRD IRPGAAFEPTYIYRL LTVNKSSLSEKGRQE	522
	3 deubiquitinase1 LVACPPMYHLMKFIP LYSKVQRPCTSTPMI DSFVRLMNEFTNMPV PPKPRQALGDKIVRD IRPGAAFEPTYIYRL LTVNKSSLSEKGRQE	537
	4 mdeubiquitinase LVACPPMYHLMKFIP LYSKVQRPCTSTPMI DSFVRLMNEFTNMPV PPKPRQALGDKIVRD IRPGAAFEPTYIYRL LTVIKSSLSEKGRQE	517


Page	7.1
			  541	      555 556	      570 571	      585 586	      600 601	      615 616	      630 
	1 pat-ML	  DAEEYLGFILNGLHE EMLrLKKLLSPirEK XiaSNGPnrrXamkE EXEkrGpGSEDEWEQ VGPnNKTSaTRQADF VQTPITGIFGGHIRS	615
	2 Deubiquitinase2 DAEEYLGFILNGLHE EMLNLKKLLSPSNEK LTISNGPKNHSVNEE EQEEQGEGSEDEWEQ VGPRNKTSVTRQADF VQTPITGIFGGHIRS	612
	3 deubiquitinase1 DAEEYLGFILNGLHE EMLNLKKLLSPSNEK LTISNGPKNHSVNEE EQEEQGEGSEDEWEQ VGPRNKTSVTRQADF VQTPITGIFGGHIRS	627
	4 mdeubiquitinase DAEEYLGFILNGLHE EMLSLKKLLSPTHEK HSVSNGPRSDLIEDE ELEDTGKGSEDEWEQ VGPKNKTSITRQADF VQTPITGIFGGHIRS	607


Page	8.1
			  631	      645 646	      660 661	      675 676	      690 691	      705 706	      720 
	1 pat-ML	  VVYQQSSKESATLQX FFTLQLDIQSDKIRT VQDALESLVARESVQ GYTTKTKQEVEaSRR VTLEKLPPVLVLHLK RFVYEKTGGCQKLaK	705
	2 Deubiquitinase2 VVYQQSSKESATLQP FFTLQLDIQSDKIRT VQDALESLVARESVQ GYTTKTKQEVEISRR VTLEKLPPVLVLHLK RFVYEKTGGCQKLIK	702
	3 deubiquitinase1 VVYQQSSKESATLQP FFTLQLDIQSDKIRT VQDALESLVARESVQ GYTTKTKQEVEISRR VTLEKLPPVLVLHLK RFVYEKTGGCQKLIK	717
	4 mdeubiquitinase VVYQQSSKESATLQL FFTLQLDIQSDKIRT VQDALESLVARESVQ GYTTKTKQEVEVSRR VTLEKLPPVLVLHLK RFVYEKTGGCQKLVK	697


Page	9.1
			  721	      735 736	      750 751	      765 766	      780 781	      795 796	      810 
	1 pat-ML	  NIkYPVDLEISnELL SPGaKNKNFKCrRTY RLFAVVYHHGNSATG GHYTTDVFQIGLNGW LRIDDQTVKVINQYQ VVKPjAkRTAYLLYY	795
	2 Deubiquitinase2 NIEYPVDLEISKELL SPGVKNKNFKCHRTY RLFAVVYHHGNSATG GHYTTDVFQIGLNGW LRIDDQTVKVINQYQ VVKPTAERTAYLLYY	792
	3 deubiquitinase1 NIEYPVDLEISKELL SPGVKNKNFKCHRTY RLFAVVYHHGNSATG GHYTTDVFQIGLNGW LRIDDQTVKVINQYQ VVKPTAERTAYLLYY	807
	4 mdeubiquitinase NIDYPVDLEISRELL SPGIKNKNFKCQRTY RLFAVVYHHGNSATG GHYTTDVFQIGLNGW LRIDDQTVKVINQYQ VVKPPADRTAYLLYY	787


Page 10.1
		  	  811	      825 826 	      840 841	      855 856 	      870 871	      885 886 	      900 
	1 pat-ML	  RRVDLL	801
	2 Deubiquitinase2 RRVDLL	798
	3 deubiquitinase1 RRVDLL	813
	4 mdeubiquitinase RRVDLL	793

Sequential Branching Clustering

pat-SB ((Deubiquitinase2 3990.00 deubiquitinase1) 3372.01 mdeubiquitinase)

Page 1.1
			  1	       15 16           30 31           45 46           60 61           75 76           90 
	1 pat-SB	  --------------- MALHrPQYIFGDFSP DEFNQFFVTPRSSVE LPPYSGTgLCjXQAX DpLPDgGQEeQRIEF GVDEVIEPSkjLPXT	75
	2 Deubiquitinase2 --------------- MALHSPQYIFGDFSP DEFNQFFVTPRSSVE LPPYSGTVLCGTQAV DKLPD-GQEYQRIEF GVDEVIEPSDTLPRT	74
	3 deubiquitinase1 REQPEDRGVPMKRAA MALHSPQYIFGDFSP DEFNQFFVTPRSSVE LPPYSGTVLCGTQAV DKLPD-GQEYQRIEF GVDEVIEPSDTLPRT	89
	4 mdeubiquitinase --------------- MALHNPQYIFGDFSP DEFNQFFVTPRSSVE LPPYSGT-LCSIQAE DELPDAGQEHQRIEF GVDEVIEPSEGLPPT	74


Page	2.1
		  	  91	      105 106	      120 121	      135 136	      150 151	      165 166	      180 
	1 pat-SB	  PSYSISSTLNPQAPE FILGCTjSKXXPkha rKkXiYjSIDgQYPh SALALkjrSNXEAEX LENDjXjGGLGQRER KKKKKRPPGYYSYLK	165
	2 Deubiquitinase2 PSYSISSTLNPQAPE FILGCTASKITPDGI TKEASYGSIDCQYPG SALALDGSSNVEAEV LENDGVSGGLGQRER KKKKKRPPGYYSYLK	164
	3 deubiquitinase1 PSYSISSTLNPQAPE FILGCTASKITPDGI TKEASYGSIDCQYPG SALALDGSSNVEAEV LENDGVSGGLGQRER KKKKKRPPGYYSYLK	179
	4 mdeubiquitinase PSYSISSTLNPQAPE FILGCTTSKKIPEAV EKDETYSSID-QYPA SALALESNSNAEAET LENDSGAGGLGQRER KKKKKRPPGYYSYLK	163


Page	3.1
			  181	      195 196	      210 211	      225 226	      240 241	      255 256	      270 
	1 pat-SB	  DGGkDSXSjXjLVNG HArSgVjrSXrAgED AEFMgDcXPjVXPRT ClSPQNjXDXaSXXV PDSPFPXjLGjDjRT AGXXEGXXXADFXQj	255
	2 Deubiquitinase2 DGGDDSISTEALVNG HANSAVPNSVSA-ED AEFMGDMPPSVTPRT CNSPQNSTDSVSDIV PDSPFPGALGSDTRT AGQPEGGPGADFGQS	253
	3 deubiquitinase1 DGGDDSISTEALVNG HANSAVPNSVSA-ED AEFMGDMPPSVTPRT CNSPQNSTDSVSDIV PDSPFPGALGSDTRT AGQPEGGPGADFGQS	268
	4 mdeubiquitinase DGGEDSASPATLVNG HATS-VGTSGEAVED AEFM-DVLPPVMPRT CDSPQNPVDFISGPV PDSPFPRTLGGDART AGLCEGCHEADFEQP	251


Page	4.1
			  271	      285 286	      300 301	      315 316	      330 331	      345 346	      360 
	1 pat-SB	  CfPAggggDiLXRTA GjQPfVGTDTTENfh VANGpILESjGEXTA jNGXELHTrEjXDLD PjKPESXSPPAkjjX SASGjcPaSQPgKSW	345
	2 Deubiquitinase2 CFPAEAGRDTLSRTA GAQPCVGTDTTENLG VANGQILESSGEGTA TNGVELHTTESIDLD PTKPESASPPADGTG SASGTLPVSQP-KSW	342
	3 deubiquitinase1 CFPAEAGRDTLSRTA GAQPCVGTDTTENLG VANGQILESSGEGTA TNGVELHTTESIDLD PTKPESASPPADGTG SASGTLPVSQP-KSW	357
	4 mdeubiquitinase CLPA----DSLLRTA GTQPYVGTDTTENFA VANGKILESPGEDTA ANGAELHTDEGADLD PAKPESQSPPAESAL SASGAIPISQPAKSW	337


Page	5.1
			  361	      375 376	      390 391	      405 406	      420 421	      435 436	      450 
	1 pat-SB	  ASLFHDSKPSjSSPc AYVETKfSPPXXSPL XSEKQcEVKEGLVPV SEDPVAIKIAELLEr VTLIHKPVSLQPRGL INKGNWCYINATLQA	435
	2 Deubiquitinase2 ASLFHDSKPSSSSPV AYVETKYSPPAISPL VSEKQVEVKEGLVPV SEDPVAIKIAELLEN VTLIHKPVSLQPRGL INKGNWCYINATLQA	432
	3 deubiquitinase1 ASLFHDSKPSSSSPV AYVETKYSPPAISPL VSEKQVEVKEGLVPV SEDPVAIKIAELLEN VTLIHKPVSLQPRGL INKGNWCYINATLQA	447
	4 mdeubiquitinase ASLFHDSKPSASSPM AYVETKCSPPVPSPL ASEKQMEVKEGLVPV SEDPVAIKIAELLET VTLIHKPVSLQPRGL INKGNWCYINATLQA	427


Page	6.1
			  451	      465 466	      480 481	      495 496	      510 511	      525 526	      540 
	1 pat-SB	  LVACPPMYHLMKFIP LYSKVQRPCTSTPMI DSFVRLMNEFTNMPV PPKPRQALGDKIVRD IRPGAAFEPTYIYRL LTVXKSSLSEKGRQE	525
	2 Deubiquitinase2 LVACPPMYHLMKFIP LYSKVQRPCTSTPMI DSFVRLMNEFTNMPV PPKPRQALGDKIVRD IRPGAAFEPTYIYRL LTVNKSSLSEKGRQE	522
	3 deubiquitinase1 LVACPPMYHLMKFIP LYSKVQRPCTSTPMI DSFVRLMNEFTNMPV PPKPRQALGDKIVRD IRPGAAFEPTYIYRL LTVNKSSLSEKGRQE	537
	4 mdeubiquitinase LVACPPMYHLMKFIP LYSKVQRPCTSTPMI DSFVRLMNEFTNMPV PPKPRQALGDKIVRD IRPGAAFEPTYIYRL LTVIKSSLSEKGRQE	517


Page	7.1
			  541	      555 556	      570 571	      585 586	      600 601	      615 616	      630 
	1 pat-SB	  DAEEYLGFILNGLHE EMLrLKKLLSPirEK XiaSNGPnrrXamkE EXEkrGpGSEDEWEQ VGPnNKTSaTRQADF VQTPITGIFGGHIRS	615
	2 Deubiquitinase2 DAEEYLGFILNGLHE EMLNLKKLLSPSNEK LTISNGPKNHSVNEE EQEEQGEGSEDEWEQ VGPRNKTSVTRQADF VQTPITGIFGGHIRS	612
	3 deubiquitinase1 DAEEYLGFILNGLHE EMLNLKKLLSPSNEK LTISNGPKNHSVNEE EQEEQGEGSEDEWEQ VGPRNKTSVTRQADF VQTPITGIFGGHIRS	627
	4 mdeubiquitinase DAEEYLGFILNGLHE EMLSLKKLLSPTHEK HSVSNGPRSDLIEDE ELEDTGKGSEDEWEQ VGPKNKTSITRQADF VQTPITGIFGGHIRS	607


Page	8.1
			  631	      645 646	      660 661	      675 676	      690 691	      705 706	      720 
	1 pat-SB	  VVYQQSSKESATLQX FFTLQLDIQSDKIRT VQDALESLVARESVQ GYTTKTKQEVEaSRR VTLEKLPPVLVLHLK RFVYEKTGGCQKLaK	705
	2 Deubiquitinase2 VVYQQSSKESATLQP FFTLQLDIQSDKIRT VQDALESLVARESVQ GYTTKTKQEVEISRR VTLEKLPPVLVLHLK RFVYEKTGGCQKLIK	702
	3 deubiquitinase1 VVYQQSSKESATLQP FFTLQLDIQSDKIRT VQDALESLVARESVQ GYTTKTKQEVEISRR VTLEKLPPVLVLHLK RFVYEKTGGCQKLIK	717
	4 mdeubiquitinase VVYQQSSKESATLQL FFTLQLDIQSDKIRT VQDALESLVARESVQ GYTTKTKQEVEVSRR VTLEKLPPVLVLHLK RFVYEKTGGCQKLVK	697


Page	9.1
			  721	      735 736	      750 751	      765 766	      780 781	      795 796	      810 
	1 pat-SB	  NIkYPVDLEISnELL SPGaKNKNFKCrRTY RLFAVVYHHGNSATG GHYTTDVFQIGLNGW LRIDDQTVKVINQYQ VVKPjAkRTAYLLYY	795
	2 Deubiquitinase2 NIEYPVDLEISKELL SPGVKNKNFKCHRTY RLFAVVYHHGNSATG GHYTTDVFQIGLNGW LRIDDQTVKVINQYQ VVKPTAERTAYLLYY	792
	3 deubiquitinase1 NIEYPVDLEISKELL SPGVKNKNFKCHRTY RLFAVVYHHGNSATG GHYTTDVFQIGLNGW LRIDDQTVKVINQYQ VVKPTAERTAYLLYY	807
	4 mdeubiquitinase NIDYPVDLEISRELL SPGIKNKNFKCQRTY RLFAVVYHHGNSATG GHYTTDVFQIGLNGW LRIDDQTVKVINQYQ VVKPPADRTAYLLYY	787


Page 10.1
		  	  811	      825 826 	      840 841	      855 856 	      870 871	      885 886	      900 
	1 pat-SB	  RRVDLL    801
	2 Deubiquitinase2 RRVDLL    798
	3 deubiquitinase1 RRVDLL    813
	4 mdeubiquitinase RRVDLL    793