PIMA Multiple Sequence Alignment Results

Maximal Linkage Clustering

pat-ML ((hyp1 8105.00 hyp2) 8061.00 hyp3)



Page 1.1
             1            15 16           30 31           45 46           60 61           75 76           90 
    1 pat-ML --------------a XENQKKLSEEWEPYI DKLVASNRTRDERVE SIQELFQKCVIEEKL PVDIFFSIFSLAFER LEEKNTLASYVIDTL     76

    2 hyp1   -------DQQGEVSV SENQKKLSEEWEPYI DKLVASNRTRDERVE SIQELFQKCVIEEKL PVDIFFSIFSLAFER LEEKNTLASYVIDTL     83
    3 hyp2   MTSLPEKDQQGEVSV SENQKKLSEEWEPYI DKLVASNRTRDERVE SIQELFQKCVIEEKL PVDIFFSIFSLAFER LEEKNTLASYVIDTL     90
    4 hyp3   ------------NII LENQKKLSEEWEPYI DKLVASNRTRDERVE SIQELFQKCVIEEKL PVDIFFSIFSLAFER LEEKNTLASYVIDTL     78



Page 2.1
             91          105 106         120 121         135 136         150 151         165 166         180 
    1 pat-ML WLFDTEWIKNFHEGS HDKAEKRLVSIGKGL KEFLPEEWLLSRLDC KFLENINVVPNGDFL NRKIVRTNTSLLYRQ KKFNLLREESEGFSH    166

    2 hyp1   WLFDTEWIKNFHEGS HDKAEKRLVSIGKGL KEFLPEEWLLSRLDC KFLENINVVPNGDFL NRKIVRTNTSLLYRQ KKFNLLREESEGFSH    173
    3 hyp2   WLFDTEWIKNFHEGS HDKAEKRLVSIGKGL KEFLPEEWLLSRLDC KFLENINVVPNGDFL NRKIVRTNTSLLYRQ KKFNLLREESEGFSH    180
    4 hyp3   WLFDTEWIKNFHEGS HDKAEKRLVSIGKGL KEFLPEEWLLSRLDC KFLENINVVPNGDFL NRKIVRTNTSLLYRQ KKFNLLREESEGFSH    168



Page 3.1
             181         195 196         210 211         225 226         240 241         255 256         270 
    1 pat-ML LMINFFDALTCLRNK SLNEDYLIVQVNKSI ISTIGAFDLDPNKVL DLILLLFSENLLDSW RFFLSILRNSPWGPN KERKFWNQLPDREKE    256

    2 hyp1   LMINFFDALTCLRNK SLNEDYLIVQVNKSI ISTIGAFDLDPNKVL DLILLLFSENLLDSW RFFLSILRNSPWGPN KERKFWNQLPDREKE    263
    3 hyp2   LMINFFDALTCLRNK SLNEDYLIVQVNKSI ISTIGAFDLDPNKVL DLILLLFSENLLDSW RFFLSILRNSPWGPN KERKFWNQLPDREKE    270
    4 hyp3   LMINFFDALTCLRNK SLNEDYLIVQVNKSI ISTIGAFDLDPNKVL DLILLLFSENLLDSW RFFLSILRNSPWGPN KERKFWNQLPDREKE    258



Page 4.1
             271         285 286         300 301         315 316         330 331         345 346         360 
    1 pat-ML TFLNNLSNANGIFNF DERFTNTKSIMSQVL GHNLQYMYKEDDENL ESYFMMVALLIKYNF ISIDNIWAHLSPSDE ELGKELGKYKDKLDE    346

    2 hyp1   TFLNNLSNANGIFNF DERFTNTKSIMSQVL GHNLQYMYKEDDENL ESYFMMVALLIKYNF ISIDNIWAHLSPSDE ELGKELGKYKDKLDE    353
    3 hyp2   TFLNNLSNANGIFNF DERFTNTKSIMSQVL GHNLQYMYKEDDENL ESYFMMVALLIKYNF ISIDNIWAHLSPSDE ELGKELGKYKDKLDE    360
    4 hyp3   TFLNNLSNANGIFNF DERFTNTKSIMSQVL GHNLQYMYKEDDENL ESYFMMVALLIKYNF ISIDNIWAHLSPSDE ELGKELGKYKDKLDE    348



Page 5.1
             361         375 376         390 391         405 406         420 421         435 436         450 
    1 pat-ML QTFKAKGNALTMAAP LPDDEIEDGETMDGQ KAEAVPEIKKAKPSQ KLGLLKSLLSIGDLS SSLLILGRYPFLLRA YPELSNLYHKLLHIS    436

    2 hyp1   QTFKAKGNALTMAAP LPDDEIEDGETMDGQ KAEAVPEIKKAKPSQ KLGLLKSLLSIGDLS SSLLILGRYPFLLRA YPELSNLYHKLLHIS    443
    3 hyp2   QTFKAKGNALTMAAP LPDDEIEDGETMDGQ KAEAVPEIKKAKPSQ KLGLLKSLLSIGDLS SSLLILGRYPFLLRA YPELSNLYHKLLHIS    450
    4 hyp3   QTFKAKGNALTMAAP LPDDEIEDGETMDGQ KAEAVPEIKKAKPSQ KLGLLKSLLSIGDLS SSLLILGRYPFLLRA YPELSNLYHKLLHIS    438



Page 6.1
             451         465 466         480 481         495 496         510 511         525 526         540 
    1 pat-ML ISSIYANYSPLKLLP NDVRERLKQPKFIPE DSRLREITLRPPKEK NLVFSLDPFADRFNK TESEVFYYFENYDED IPILRNLTEFYNIAI    526

    2 hyp1   ISSIYANYSPLKLLP NDVRERLKQPKFIPE DSRLREITLRPPKEK NLVFSLDPFADRFNK TESEVFYYFENYDED IPILRNLTEFYNIAI    533
    3 hyp2   ISSIYANYSPLKLLP NDVRERLKQPKFIPE DSRLREITLRPPKEK NLVFSLDPFADRFNK TESEVFYYFENYDED IPILRNLTEFYNIAI    540
    4 hyp3   ISSIYANYSPLKLLP NDVRERLKQPKFIPE DSRLREITLRPPKEK NLVFSLDPFADRFNK TESEVFYYFENYDED IPILRNLTEFYNIAI    528



Page 7.1
             541         555 556         570 571         585 586         600 601         615 616         630 
    1 pat-ML PWLRLSGLALCHDPV IVTKLCRIGQKCVDN SSESRTLWLDIIRSL LLPLITLIDVNTGLS YELFELLSKFDSSTR YALYGEWSSTSMKKF    616

    2 hyp1   PWLRLSGLALCHDPV IVTKLCRIGQKCVDN SSESRTLWLDIIRSL LLPLITLIDVNTGLS YELFELLSKFDSSTR YALYGEWSSTSMKKF    623
    3 hyp2   PWLRLSGLALCHDPV IVTKLCRIGQKCVDN SSESRTLWLDIIRSL LLPLITLIDVNTGLS YELFELLSKFDSSTR YALYGEWSSTSMKKF    630
    4 hyp3   PWLRLSGLALCHDPV IVTKLCRIGQKCVDN SSESRTLWLDIIRSL LLPLITLIDVNTGLS YELFELLSKFDSSTR YALYGEWSSTSMKKF    618



Page 8.1
             631         645 646         660 661         675 676         690 691         705 706         720 
    1 pat-ML PELKLQNSITEKETK GILRRLTKTNVKQFG RLLAKVCHSNPCTVF SIALNQIETYDNLVE VVVDSARFITALDFD ALTFIILSSFSNEFK    706

    2 hyp1   PELKLQNSITEKETK GILRRLTKTNVKQFG RLLAKVCHSNPCTVF SIALNQIETYDNLVE VVVDSARFITALDFD ALTFIILSSFSNEFK    713
    3 hyp2   PELKLQNSITEKETK GILRRLTKTNVKQFG RLLAKVCHSNPCTVF SIALNQIETYDNLVE VVVDSARFITALDFD ALTFIILSSFSNEFK    720
    4 hyp3   PELKLQNSITEKETK GILRRLTKTNVKQFG RLLAKVCHSNPCTVF SIALNQIETYDNLVE VVVDSARFITALDFD ALTFIILSSFSNEFK    708



Page 9.1
             721         735 736         750 751         765 766         780 781         795 796         810 
    1 pat-ML KRLKSDGTSIAHWLQ GLASFCGRVFRRYSS LDCTSIVEYVIKQFK VNQMFDLVILKELLS QMTGLQPWTNLSDNQ IQGAAGGPVLRQLSL    796

    2 hyp1   KRLKSDGTSIAHWLQ GLASFCGRVFRRYSS LDCTSIVEYVIKQFK VNQMFDLVILKELLS QMTGLQPWTNLSDNQ IQGAAGGPVLRQLSL    803
    3 hyp2   KRLKSDGTSIAHWLQ GLASFCGRVFRRYSS LDCTSIVEYVIKQFK VNQMFDLVILKELLS QMTGLQPWTNLSDNQ IQGAAGGPVLRQLSL    810
    4 hyp3   KRLKSDGTSIAHWLQ GLASFCGRVFRRYSS LDCTSIVEYVIKQFK VNQMFDLVILKELLS QMTGLQPWTNLSDNQ IQGAAGGPVLRQLSL    798



Page 10.1
             811         825 826         840 841         855 856         870 871         885 886         900 
    1 pat-ML SLIYENPDVVRKSSM RLFNTLQKNGLATQL LVLLSQKYSTCIYDV TDENSHLKLISSLQD ECSDVLYLLMEFLNM VCSPKSYYKLIPSFE    886

    2 hyp1   SLIYENPDVVRKSSM RLFNTLQKNGLATQL LVLLSQKYSTCIYDV TDENSHLKLISSLQD ECSDVLYLLMEFLNM VCSPKSYYKLIPSFE    893
    3 hyp2   SLIYENPDVVRKSSM RLFNTLQKNGLATQL LVLLSQKYSTCIYDV TDENSHLKLISSLQD ECSDVLYLLMEFLNM VCSPKSYYKLIPSFE    900
    4 hyp3   SLIYENPDVVRKSSM RLFNTLQKNGLATQL LVLLSQKYSTCIYDV TDENSHLKLISSLQD ECSDVLYLLMEFLNM VCSPKSYYKLIPSFE    888



Page 11.1
             901         915 916         930 931         945 946         960 961         975 976         990 
    1 pat-ML QLIQDFHIQPQVAFY LSRYKNLDHSLTGSN TEDAMDIDYENTSSP NTASNPVWSIDNSVI TELLPKQIWDYFSPN FYLTFWKLSLYDVFV    976

    2 hyp1   QLIQDFHIQPQVAFY LSRYKNLDHSLTGSN TEDAMDIDYENTSSP NTASNPVWSIDNSVI TELLPKQIWDYFSPN FYLTFWKLSLYDVFV    983
    3 hyp2   QLIQDFHIQPQVAFY LSRYKNLDHSLTGSN TEDAMDIDYENTSSP NTASNPVWSIDNSVI TELLPKQIWDYFSPN FYLTFWKLSLYDVFV    990
    4 hyp3   QLIQDFHIQPQVAFY LSRYKNLDHSLTGSN TEDAMDIDYENTSSP NTASNPVWSIDNSVI TELLPKQIWDYFSPN FYLTFWKLSLYDVFV    978



Page 12.1
             991        1005 1006       1020 1021       1035 1036       1050 1051       1065 1066       1080 
    1 pat-ML PLERYEFERSRAFDQ IRQTDAANTFYSRHR HDRQKIMQLSNSLQN ELKEHINSLESVRKV LQGDCVKWFIPNGVF PNGTRLEHARFNCAR   1066

    2 hyp1   PLERYEFERSRAFDQ IRQTDAANTFYSRHR HDRQKIMQLSNSLQN ELKEHINSLESVRKV LQGDCVKWFIPNGVF PNGTRLEHARFNCAR   1073
    3 hyp2   PLERYEFERSRAFDQ IRQTDAANTFYSRHR HDRQKIMQLSNSLQN ELKEHINSLESVRKV LQGDCVKWFIPNGVF PNGTRLEHARFNCAR   1080
    4 hyp3   PLERYEFERSRAFDQ IRQTDAANTFYSRHR HDRQKIMQLSNSLQN ELKEHINSLESVRKV LQGDCVKWFIPNGVF PNGTRLEHARFNCAR   1068



Page 13.1
             1081       1095 1096       1110 1111       1125 1126       1140 1141       1155 1156       1170 
    1 pat-ML YLWTLCIAPRLKMSP HDALYCAKFVKLLHS LGTPNFSTMSFLEIL FNSQLPSFIFSMTQR EADNFGRFLYEVLYD ITSWYRDKILYEREC   1156

    2 hyp1   YLWTLCIAPRLKMSP HDALYCAKFVKLLHS LGTPNFSTMSFLEIL FNSQLPSFIFSMTQR EADNFGRFLYEVLYD ITSWYRDKILYEREC   1163
    3 hyp2   YLWTLCIAPRLKMSP HDALYCAKFVKLLHS LGTPNFSTMSFLEIL FNSQLPSFIFSMTQR EADNFGRFLYEVLYD ITSWYRDKILYEREC   1170
    4 hyp3   YLWTLCIAPRLKMSP HDALYCAKFVKLLHS LGTPNFSTMSFLEIL FNSQLPSFIFSMTQR EADNFGRFLYEVLYD ITSWYRDKILYEREC   1158



Page 14.1
             1171       1185 1186       1200 1201       1215 1216       1230 1231       1245 1246       1260 
    1 pat-ML LANGALPGFRLYWSD EQNDPDLSAVLPYNK FVLLFSKWHKYLTSY FESCLLSTEYMHIYN SVIILEKILPCFPLI IESGSALKRAAERLK   1246

    2 hyp1   LANGALPGFRLYWSD EQNDPDLSAVLPYNK FVLLFSKWHKYLTSY FESCLLSTEYMHIYN SVIILEKILPCFPLI IESGSALKRAAERLK   1253
    3 hyp2   LANGALPGFRLYWSD EQNDPDLSAVLPYNK FVLLFSKWHKYLTSY FESCLLSTEYMHIYN SVIILEKILPCFPLI IESGSALKRAAERLK   1260
    4 hyp3   LANGALPGFRLYWSD EQNDPDLSAVLPYNK FVLLFSKWHKYLTSY FESCLLSTEYMHIYN SVIILEKILPCFPLI IESGSALKRAAERLK   1248



Page 15.1
             1261       1275 1276       1290 1291       1305 1306       1320 1321       1335 1336       1350 
    1 pat-ML DEEKREDLKVLALGY FAKLSKKQPEWVSFN SFSGTVRPSNSEKLQ RPQQLSVAATSAVDS KTASISEEQAKIDKQ KVALNPSAPEFVPDS   1336

    2 hyp1   DEEKREDLKVLALGY FAKLSKKQPEWVSFN SFSGTVRPSNSEKLQ RPQQLSVAATSAVDS KTASISEEQAKIDKQ KVALNPSAPEFVPDS   1343
    3 hyp2   DEEKREDLKVLALGY FAKLSKKQPEWVSFN SFSGTVRPSNSEKLQ RPQQLSVAATSAVDS KTASISEEQAKIDKQ KVALNPSAPEFVPDS   1350
    4 hyp3   DEEKREDLKVLALGY FAKLSKKQPEWVSFN SFSGTVRPSNSEKLQ RPQQLSVAATSAVDS KTASISEEQAKIDKQ KVALNPSAPEFVPDS   1338



Page 16.1
             1351       1365 1366       1380 1381       1395 1396       1410 1411       1425 1426       1440 
    1 pat-ML TPSDAVASETDNKNL VENKAVEKRVEARSS ANERKQEERRRKTTP EGNRRALRTRTPTNE DIQRSDSKLREDQSR DRTPQSRSFTNENND   1426

    2 hyp1   TPSDAVASETDNKNL VENKAVEKRVEARSS ANERKQEERRRKTTP EGNRRALRTRTPTNE DIQRSDSKLREDQSR DRTPQSRSFTNENND   1433
    3 hyp2   TPSDAVASETDNKNL VENKAVEKRVEARSS ANERKQEERRRKTTP EGNRRALRTRTPTNE DIQRSDSKLREDQSR DRTPQSRSFTNENND   1440
    4 hyp3   TPSDAVASETDNKNL VENKAVEKRVEARSS ANERKQEERRRKTTP EGNRRALRTRTPTNE DIQRSDSKLREDQSR DRTPQSRSFTNENND   1428



Page 17.1
             1441       1455 1456       1470 1471       1485 1486       1500 1501       1515 1516       1530 
    1 pat-ML NLRSVSRHTRREPQQ AQNLNARREHESQKS DRWRQNGNVNRNPRV SNNNSTNVSRERSSE ANHRTSNDNKRDEVT EGKDKNKRQDISGES   1516

    2 hyp1   NLRSVSRHTRREPQQ AQNLNARREHESQKS DRWRQNGNVNRNPRV SNNNSTNVSRERSSE ANHRTSNDNKRDEVT EGKDKNKRQDISGES   1523
    3 hyp2   NLRSVSRHTRREPQQ AQNLNARREHESQKS DRWRQNGNVNRNPRV SNNNSTNVSRERSSE ANHRTSNDNKRDEVT EGKDKNKRQDISGES   1530
    4 hyp3   NLRSVSRHTRREPQQ AQNLNARREHESQKS DRWRQNGNVNRNPRV SNNNSTNVSRERSSE ANHRTSNDNKRDEVT EGKDKNKRQDISGES   1518



Page 18.1
             1531       1545 1546       1560 1561       1575 1576       1590 1591       1605 1606       1620 
    1 pat-ML NSRQNNAISRAGRSN GSNRGNDSRDADGRR STHYASNKRPRSSDS QSPSNLREEDERENS RRRARQDDRRDRDSR QQRDRPRDRTSRSAR   1606

    2 hyp1   NSRQNNAISRAGRSN GSNRGNDSRDADGRR STHYASNKRPRSSDS QSPSNLREEDERENS RRRARQDDRRDRDSR QQRDRPRDRTSRSAR   1613
    3 hyp2   NSRQNNAISRAGRSN GSNRGNDSRDADGRR STHYASNKRPRSSDS QSPSNLREEDERENS RRRARQDDRRDRDSR QQRDRPRDRTSRSAR   1620
    4 hyp3   NSRQNNAISRAGRSN GSNRGNDSRDADGRR STHYASNKRPRSSDS QSPSNLREEDERENS RRRARQDDRRDRDSR QQRDRPRDRTSRSAR   1608



Page 19.1
             1621       1635 1636       1650 1651       1665 1666       1680 1681       1695 1696       1710 
    1 pat-ML EEKRRKIQ   1614

    2 hyp1   EEKRRKIQ   1621
    3 hyp2   EEKRRKIQ   1628
    4 hyp3   EEKRRKIQ   1616

Sequential Branching Clustering

pat-SB ((hyp1 8105.00 hyp2) 8061.00 hyp3)



Page 1.1
             1            15 16           30 31           45 46           60 61           75 76           90 
    1 pat-SB --------------a XENQKKLSEEWEPYI DKLVASNRTRDERVE SIQELFQKCVIEEKL PVDIFFSIFSLAFER LEEKNTLASYVIDTL     76

    2 hyp1   -------DQQGEVSV SENQKKLSEEWEPYI DKLVASNRTRDERVE SIQELFQKCVIEEKL PVDIFFSIFSLAFER LEEKNTLASYVIDTL     83
    3 hyp2   MTSLPEKDQQGEVSV SENQKKLSEEWEPYI DKLVASNRTRDERVE SIQELFQKCVIEEKL PVDIFFSIFSLAFER LEEKNTLASYVIDTL     90
    4 hyp3   ------------NII LENQKKLSEEWEPYI DKLVASNRTRDERVE SIQELFQKCVIEEKL PVDIFFSIFSLAFER LEEKNTLASYVIDTL     78



Page 2.1
             91          105 106         120 121         135 136         150 151         165 166         180 
    1 pat-SB WLFDTEWIKNFHEGS HDKAEKRLVSIGKGL KEFLPEEWLLSRLDC KFLENINVVPNGDFL NRKIVRTNTSLLYRQ KKFNLLREESEGFSH    166

    2 hyp1   WLFDTEWIKNFHEGS HDKAEKRLVSIGKGL KEFLPEEWLLSRLDC KFLENINVVPNGDFL NRKIVRTNTSLLYRQ KKFNLLREESEGFSH    173
    3 hyp2   WLFDTEWIKNFHEGS HDKAEKRLVSIGKGL KEFLPEEWLLSRLDC KFLENINVVPNGDFL NRKIVRTNTSLLYRQ KKFNLLREESEGFSH    180
    4 hyp3   WLFDTEWIKNFHEGS HDKAEKRLVSIGKGL KEFLPEEWLLSRLDC KFLENINVVPNGDFL NRKIVRTNTSLLYRQ KKFNLLREESEGFSH    168



Page 3.1
             181         195 196         210 211         225 226         240 241         255 256         270 
    1 pat-SB LMINFFDALTCLRNK SLNEDYLIVQVNKSI ISTIGAFDLDPNKVL DLILLLFSENLLDSW RFFLSILRNSPWGPN KERKFWNQLPDREKE    256

    2 hyp1   LMINFFDALTCLRNK SLNEDYLIVQVNKSI ISTIGAFDLDPNKVL DLILLLFSENLLDSW RFFLSILRNSPWGPN KERKFWNQLPDREKE    263
    3 hyp2   LMINFFDALTCLRNK SLNEDYLIVQVNKSI ISTIGAFDLDPNKVL DLILLLFSENLLDSW RFFLSILRNSPWGPN KERKFWNQLPDREKE    270
    4 hyp3   LMINFFDALTCLRNK SLNEDYLIVQVNKSI ISTIGAFDLDPNKVL DLILLLFSENLLDSW RFFLSILRNSPWGPN KERKFWNQLPDREKE    258



Page 4.1
             271         285 286         300 301         315 316         330 331         345 346         360 
    1 pat-SB TFLNNLSNANGIFNF DERFTNTKSIMSQVL GHNLQYMYKEDDENL ESYFMMVALLIKYNF ISIDNIWAHLSPSDE ELGKELGKYKDKLDE    346

    2 hyp1   TFLNNLSNANGIFNF DERFTNTKSIMSQVL GHNLQYMYKEDDENL ESYFMMVALLIKYNF ISIDNIWAHLSPSDE ELGKELGKYKDKLDE    353
    3 hyp2   TFLNNLSNANGIFNF DERFTNTKSIMSQVL GHNLQYMYKEDDENL ESYFMMVALLIKYNF ISIDNIWAHLSPSDE ELGKELGKYKDKLDE    360
    4 hyp3   TFLNNLSNANGIFNF DERFTNTKSIMSQVL GHNLQYMYKEDDENL ESYFMMVALLIKYNF ISIDNIWAHLSPSDE ELGKELGKYKDKLDE    348



Page 5.1
             361         375 376         390 391         405 406         420 421         435 436         450 
    1 pat-SB QTFKAKGNALTMAAP LPDDEIEDGETMDGQ KAEAVPEIKKAKPSQ KLGLLKSLLSIGDLS SSLLILGRYPFLLRA YPELSNLYHKLLHIS    436

    2 hyp1   QTFKAKGNALTMAAP LPDDEIEDGETMDGQ KAEAVPEIKKAKPSQ KLGLLKSLLSIGDLS SSLLILGRYPFLLRA YPELSNLYHKLLHIS    443
    3 hyp2   QTFKAKGNALTMAAP LPDDEIEDGETMDGQ KAEAVPEIKKAKPSQ KLGLLKSLLSIGDLS SSLLILGRYPFLLRA YPELSNLYHKLLHIS    450
    4 hyp3   QTFKAKGNALTMAAP LPDDEIEDGETMDGQ KAEAVPEIKKAKPSQ KLGLLKSLLSIGDLS SSLLILGRYPFLLRA YPELSNLYHKLLHIS    438



Page 6.1
             451         465 466         480 481         495 496         510 511         525 526         540 
    1 pat-SB ISSIYANYSPLKLLP NDVRERLKQPKFIPE DSRLREITLRPPKEK NLVFSLDPFADRFNK TESEVFYYFENYDED IPILRNLTEFYNIAI    526

    2 hyp1   ISSIYANYSPLKLLP NDVRERLKQPKFIPE DSRLREITLRPPKEK NLVFSLDPFADRFNK TESEVFYYFENYDED IPILRNLTEFYNIAI    533
    3 hyp2   ISSIYANYSPLKLLP NDVRERLKQPKFIPE DSRLREITLRPPKEK NLVFSLDPFADRFNK TESEVFYYFENYDED IPILRNLTEFYNIAI    540
    4 hyp3   ISSIYANYSPLKLLP NDVRERLKQPKFIPE DSRLREITLRPPKEK NLVFSLDPFADRFNK TESEVFYYFENYDED IPILRNLTEFYNIAI    528



Page 7.1
             541         555 556         570 571         585 586         600 601         615 616         630 
    1 pat-SB PWLRLSGLALCHDPV IVTKLCRIGQKCVDN SSESRTLWLDIIRSL LLPLITLIDVNTGLS YELFELLSKFDSSTR YALYGEWSSTSMKKF    616

    2 hyp1   PWLRLSGLALCHDPV IVTKLCRIGQKCVDN SSESRTLWLDIIRSL LLPLITLIDVNTGLS YELFELLSKFDSSTR YALYGEWSSTSMKKF    623
    3 hyp2   PWLRLSGLALCHDPV IVTKLCRIGQKCVDN SSESRTLWLDIIRSL LLPLITLIDVNTGLS YELFELLSKFDSSTR YALYGEWSSTSMKKF    630
    4 hyp3   PWLRLSGLALCHDPV IVTKLCRIGQKCVDN SSESRTLWLDIIRSL LLPLITLIDVNTGLS YELFELLSKFDSSTR YALYGEWSSTSMKKF    618



Page 8.1
             631         645 646         660 661         675 676         690 691         705 706         720 
    1 pat-SB PELKLQNSITEKETK GILRRLTKTNVKQFG RLLAKVCHSNPCTVF SIALNQIETYDNLVE VVVDSARFITALDFD ALTFIILSSFSNEFK    706

    2 hyp1   PELKLQNSITEKETK GILRRLTKTNVKQFG RLLAKVCHSNPCTVF SIALNQIETYDNLVE VVVDSARFITALDFD ALTFIILSSFSNEFK    713
    3 hyp2   PELKLQNSITEKETK GILRRLTKTNVKQFG RLLAKVCHSNPCTVF SIALNQIETYDNLVE VVVDSARFITALDFD ALTFIILSSFSNEFK    720
    4 hyp3   PELKLQNSITEKETK GILRRLTKTNVKQFG RLLAKVCHSNPCTVF SIALNQIETYDNLVE VVVDSARFITALDFD ALTFIILSSFSNEFK    708



Page 9.1
             721         735 736         750 751         765 766         780 781         795 796         810 
    1 pat-SB KRLKSDGTSIAHWLQ GLASFCGRVFRRYSS LDCTSIVEYVIKQFK VNQMFDLVILKELLS QMTGLQPWTNLSDNQ IQGAAGGPVLRQLSL    796

    2 hyp1   KRLKSDGTSIAHWLQ GLASFCGRVFRRYSS LDCTSIVEYVIKQFK VNQMFDLVILKELLS QMTGLQPWTNLSDNQ IQGAAGGPVLRQLSL    803
    3 hyp2   KRLKSDGTSIAHWLQ GLASFCGRVFRRYSS LDCTSIVEYVIKQFK VNQMFDLVILKELLS QMTGLQPWTNLSDNQ IQGAAGGPVLRQLSL    810
    4 hyp3   KRLKSDGTSIAHWLQ GLASFCGRVFRRYSS LDCTSIVEYVIKQFK VNQMFDLVILKELLS QMTGLQPWTNLSDNQ IQGAAGGPVLRQLSL    798



Page 10.1
             811         825 826         840 841         855 856         870 871         885 886         900 
    1 pat-SB SLIYENPDVVRKSSM RLFNTLQKNGLATQL LVLLSQKYSTCIYDV TDENSHLKLISSLQD ECSDVLYLLMEFLNM VCSPKSYYKLIPSFE    886

    2 hyp1   SLIYENPDVVRKSSM RLFNTLQKNGLATQL LVLLSQKYSTCIYDV TDENSHLKLISSLQD ECSDVLYLLMEFLNM VCSPKSYYKLIPSFE    893
    3 hyp2   SLIYENPDVVRKSSM RLFNTLQKNGLATQL LVLLSQKYSTCIYDV TDENSHLKLISSLQD ECSDVLYLLMEFLNM VCSPKSYYKLIPSFE    900
    4 hyp3   SLIYENPDVVRKSSM RLFNTLQKNGLATQL LVLLSQKYSTCIYDV TDENSHLKLISSLQD ECSDVLYLLMEFLNM VCSPKSYYKLIPSFE    888



Page 11.1
             901         915 916         930 931         945 946         960 961         975 976         990 
    1 pat-SB QLIQDFHIQPQVAFY LSRYKNLDHSLTGSN TEDAMDIDYENTSSP NTASNPVWSIDNSVI TELLPKQIWDYFSPN FYLTFWKLSLYDVFV    976

    2 hyp1   QLIQDFHIQPQVAFY LSRYKNLDHSLTGSN TEDAMDIDYENTSSP NTASNPVWSIDNSVI TELLPKQIWDYFSPN FYLTFWKLSLYDVFV    983
    3 hyp2   QLIQDFHIQPQVAFY LSRYKNLDHSLTGSN TEDAMDIDYENTSSP NTASNPVWSIDNSVI TELLPKQIWDYFSPN FYLTFWKLSLYDVFV    990
    4 hyp3   QLIQDFHIQPQVAFY LSRYKNLDHSLTGSN TEDAMDIDYENTSSP NTASNPVWSIDNSVI TELLPKQIWDYFSPN FYLTFWKLSLYDVFV    978



Page 12.1
             991        1005 1006       1020 1021       1035 1036       1050 1051       1065 1066       1080 
    1 pat-SB PLERYEFERSRAFDQ IRQTDAANTFYSRHR HDRQKIMQLSNSLQN ELKEHINSLESVRKV LQGDCVKWFIPNGVF PNGTRLEHARFNCAR   1066

    2 hyp1   PLERYEFERSRAFDQ IRQTDAANTFYSRHR HDRQKIMQLSNSLQN ELKEHINSLESVRKV LQGDCVKWFIPNGVF PNGTRLEHARFNCAR   1073
    3 hyp2   PLERYEFERSRAFDQ IRQTDAANTFYSRHR HDRQKIMQLSNSLQN ELKEHINSLESVRKV LQGDCVKWFIPNGVF PNGTRLEHARFNCAR   1080
    4 hyp3   PLERYEFERSRAFDQ IRQTDAANTFYSRHR HDRQKIMQLSNSLQN ELKEHINSLESVRKV LQGDCVKWFIPNGVF PNGTRLEHARFNCAR   1068



Page 13.1
             1081       1095 1096       1110 1111       1125 1126       1140 1141       1155 1156       1170 
    1 pat-SB YLWTLCIAPRLKMSP HDALYCAKFVKLLHS LGTPNFSTMSFLEIL FNSQLPSFIFSMTQR EADNFGRFLYEVLYD ITSWYRDKILYEREC   1156

    2 hyp1   YLWTLCIAPRLKMSP HDALYCAKFVKLLHS LGTPNFSTMSFLEIL FNSQLPSFIFSMTQR EADNFGRFLYEVLYD ITSWYRDKILYEREC   1163
    3 hyp2   YLWTLCIAPRLKMSP HDALYCAKFVKLLHS LGTPNFSTMSFLEIL FNSQLPSFIFSMTQR EADNFGRFLYEVLYD ITSWYRDKILYEREC   1170
    4 hyp3   YLWTLCIAPRLKMSP HDALYCAKFVKLLHS LGTPNFSTMSFLEIL FNSQLPSFIFSMTQR EADNFGRFLYEVLYD ITSWYRDKILYEREC   1158



Page 14.1
             1171       1185 1186       1200 1201       1215 1216       1230 1231       1245 1246       1260 
    1 pat-SB LANGALPGFRLYWSD EQNDPDLSAVLPYNK FVLLFSKWHKYLTSY FESCLLSTEYMHIYN SVIILEKILPCFPLI IESGSALKRAAERLK   1246

    2 hyp1   LANGALPGFRLYWSD EQNDPDLSAVLPYNK FVLLFSKWHKYLTSY FESCLLSTEYMHIYN SVIILEKILPCFPLI IESGSALKRAAERLK   1253
    3 hyp2   LANGALPGFRLYWSD EQNDPDLSAVLPYNK FVLLFSKWHKYLTSY FESCLLSTEYMHIYN SVIILEKILPCFPLI IESGSALKRAAERLK   1260
    4 hyp3   LANGALPGFRLYWSD EQNDPDLSAVLPYNK FVLLFSKWHKYLTSY FESCLLSTEYMHIYN SVIILEKILPCFPLI IESGSALKRAAERLK   1248



Page 15.1
             1261       1275 1276       1290 1291       1305 1306       1320 1321       1335 1336       1350 
    1 pat-SB DEEKREDLKVLALGY FAKLSKKQPEWVSFN SFSGTVRPSNSEKLQ RPQQLSVAATSAVDS KTASISEEQAKIDKQ KVALNPSAPEFVPDS   1336

    2 hyp1   DEEKREDLKVLALGY FAKLSKKQPEWVSFN SFSGTVRPSNSEKLQ RPQQLSVAATSAVDS KTASISEEQAKIDKQ KVALNPSAPEFVPDS   1343
    3 hyp2   DEEKREDLKVLALGY FAKLSKKQPEWVSFN SFSGTVRPSNSEKLQ RPQQLSVAATSAVDS KTASISEEQAKIDKQ KVALNPSAPEFVPDS   1350
    4 hyp3   DEEKREDLKVLALGY FAKLSKKQPEWVSFN SFSGTVRPSNSEKLQ RPQQLSVAATSAVDS KTASISEEQAKIDKQ KVALNPSAPEFVPDS   1338



Page 16.1
             1351       1365 1366       1380 1381       1395 1396       1410 1411       1425 1426       1440 
    1 pat-SB TPSDAVASETDNKNL VENKAVEKRVEARSS ANERKQEERRRKTTP EGNRRALRTRTPTNE DIQRSDSKLREDQSR DRTPQSRSFTNENND   1426

    2 hyp1   TPSDAVASETDNKNL VENKAVEKRVEARSS ANERKQEERRRKTTP EGNRRALRTRTPTNE DIQRSDSKLREDQSR DRTPQSRSFTNENND   1433
    3 hyp2   TPSDAVASETDNKNL VENKAVEKRVEARSS ANERKQEERRRKTTP EGNRRALRTRTPTNE DIQRSDSKLREDQSR DRTPQSRSFTNENND   1440
    4 hyp3   TPSDAVASETDNKNL VENKAVEKRVEARSS ANERKQEERRRKTTP EGNRRALRTRTPTNE DIQRSDSKLREDQSR DRTPQSRSFTNENND   1428



Page 17.1
             1441       1455 1456       1470 1471       1485 1486       1500 1501       1515 1516       1530 
    1 pat-SB NLRSVSRHTRREPQQ AQNLNARREHESQKS DRWRQNGNVNRNPRV SNNNSTNVSRERSSE ANHRTSNDNKRDEVT EGKDKNKRQDISGES   1516

    2 hyp1   NLRSVSRHTRREPQQ AQNLNARREHESQKS DRWRQNGNVNRNPRV SNNNSTNVSRERSSE ANHRTSNDNKRDEVT EGKDKNKRQDISGES   1523
    3 hyp2   NLRSVSRHTRREPQQ AQNLNARREHESQKS DRWRQNGNVNRNPRV SNNNSTNVSRERSSE ANHRTSNDNKRDEVT EGKDKNKRQDISGES   1530
    4 hyp3   NLRSVSRHTRREPQQ AQNLNARREHESQKS DRWRQNGNVNRNPRV SNNNSTNVSRERSSE ANHRTSNDNKRDEVT EGKDKNKRQDISGES   1518



Page 18.1
             1531       1545 1546       1560 1561       1575 1576       1590 1591       1605 1606       1620 
    1 pat-SB NSRQNNAISRAGRSN GSNRGNDSRDADGRR STHYASNKRPRSSDS QSPSNLREEDERENS RRRARQDDRRDRDSR QQRDRPRDRTSRSAR   1606

    2 hyp1   NSRQNNAISRAGRSN GSNRGNDSRDADGRR STHYASNKRPRSSDS QSPSNLREEDERENS RRRARQDDRRDRDSR QQRDRPRDRTSRSAR   1613
    3 hyp2   NSRQNNAISRAGRSN GSNRGNDSRDADGRR STHYASNKRPRSSDS QSPSNLREEDERENS RRRARQDDRRDRDSR QQRDRPRDRTSRSAR   1620
    4 hyp3   NSRQNNAISRAGRSN GSNRGNDSRDADGRR STHYASNKRPRSSDS QSPSNLREEDERENS RRRARQDDRRDRDSR QQRDRPRDRTSRSAR   1608



Page 19.1
             1621       1635 1636       1650 1651       1665 1666       1680 1681       1695 1696       1710 
    1 pat-SB EEKRRKIQ   1614

    2 hyp1   EEKRRKIQ   1621
    3 hyp2   EEKRRKIQ   1628
    4 hyp3   EEKRRKIQ   1616